The population of Rochester, the county seat of Monroe County and the fourth-largest city in New York after New York City, Buffalo, and Yonkers, was 211,328 in 2020, according to the United States Census. Rochester, located in Western New York, serves as the center of a broader metropolitan area that spans six counties and is home to one million people. Rochester was among the first boomtowns in the United States, thanks to the fertile Genesee River Valley and numerous flour mills, as well as its status as a manufacturing hub that spurred even more rapid population growth.

Rochester is home to various local and national enterprises like Carestream Health and many Fortune 1000 companies such as Paychex. Despite relocating its headquarters to Norwalk, Connecticut, Xerox still has a substantial presence in Rochester, where it was first established in 1906 as the Haloid Company[92]. In 2014, Bausch & Lomb moved to Bridgewater, New Jersey. Although Frank Gannett and Hiram Sibley started their businesses in Rochester, Western Union and the Gannett newspaper firm have since moved away.

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