The Commonwealth of Kentucky is home to the populous city of Louisville, which holds the distinction of being the sixth-most populous city in the Southeastern United States and the 28th most populous city in the entire country. Louisville has served as the historical and nominal seat of Jefferson County since 2003 and is situated on the border of Indiana.

The city was established in 1778 by George Rogers Clark and named after King Louis XVI of France. As one of the oldest cities west of the Appalachians, Louisville thrived as a portage site due to the nearby Falls of Ohio, which was the primary obstruction to river traffic between the upper Ohio River and the Gulf of Mexico.Louisville is renowned for its contributions to American culture and history, including being the birthplace of iconic boxer Muhammad Ali, the host city of the acclaimed Kentucky Derby, and the origin of Kentucky Fried Chicken. It is also home to the esteemed University of Louisville and its Cardinals, as well as the legendary Louisville Slugger baseball

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